متحسس ZnO/CuO النانوي الوظيفي الحيوي للتقدير الجهدي لهيدروكلوريد السيودوإيفيدرين في المنتجات النقية والتجارية
DOI:
https://doi.org/10.21123/bsj.2024.9313الكلمات المفتاحية:
هيدروكلوريد السيدوإيفيدرين، مركب أكسيد الزنك/النحاس النانوي، متحسس بوليمري، شجرة الليوسينا Lucaena leucocephala، الكيمياء الخضراءالملخص
لقد ولدت الإمكانيات الوظيفية الفائقة لأكاسيد الزنك (ZnO) والنحاس (CuO) النانوية اهتمامًا كبيرًا باستخدام أكاسيد المعادن مثل المركبات النانوية المميزة والنشطة كهربائيًا في الدراسات المتعلقة بالقياسات الجهدية والمتحسسات. تم تحضير هذه الأكاسيد النانوية من مستخلص بذور شجرة الليوسينا (Leucaena leucocephala) كطريقة صديقة للبيئة. إذ تم اقتراح تطوير متحسس غشائي من أسلاك النحاس المطلية بمركب نانوي ZnO/CuO كطريقة جديدة للتقدير الجهدي لهيدروكلوريد السيدوإيفيدرين (PSD) في أشكاله النقية وجرعاتها الصيدلانية. بوجود كلوريد البولي فينيل (PVC) كبوليمر ذو وزن جزيئي عالي و"أورثو- نيتروفينيل أوكتيل إيثر (o-NPOE) كوسيط مذيب، تم دمج PSD مع حمض الفوسفوتونجستيك (PTA) لإنتاج هيدروكلوريد السيدوإيفيدرين- فوسفوتونجستات ( PSD-PT) كأساس للتحسس. أظهر المتحسس المحور حساسية وانتقائية عالية جدًا لتقدير وقياس PSD بعلاقة خطية تبلغ 1.0×10-8 -1.0 ×10-2 مول لتر-1. وأظهرت معادلة الخط المستقيم (معادلة الإنحدار) EmV = (-58.143) log [PSD] + 526.71. وباستخدام المتحسس المقترح، يمكن تقديرهيدروكلوريد السيدوإيفيدرين بشكل فعال في أشكاله النقية والمنتجات والتجارية.
Received 09/09/2023
Revised 22/10/2023
Accepted 24/10/2023
Published Online First 20/03/2024
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الحقوق الفكرية (c) 2024 Fadam M. Abdoon, Sarhan A. Salman, Hasan M. Hasan, Suham T. Ameen, Maha F. El-Tohamy
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