تثبيط نمو الزوائف الزنجارية باستخدام منتجات بعض الاحياء العلاجية ونواتج الايض الثانوي لمستخلصات نبات المر المقدرة بتقنية كروموتوغرافيا الغاز
محتوى المقالة الرئيسي
الملخص
ان محدودية توفر العلاجات الفعالة لمعالجة البكتريا، والبحث عن عوامل جديدة مضادة للبكتيريا أمر ضروري. لذلك هدفت الدراسة الحالية الى استخدام تأثيرنواتج بعض الاحياء العلاجية مثل Lactobacillus acidophilus و Saccharomyces boulardii المنماة في الأوساط الصلبة والسائلة، وكذلك فحص النشاط الحيوي لنواتج الايض الثانوي للمستخلصات المائية والكحولية والخل لنبات Commiphora myrrha (المر) على نمو خمس عزلات من الزوائف الزنجارية المعزولة من الجروح باستخدام طريقة الانتشار بالاقراص. اظهرت بعض الاختبارات الكيميائية على وجود عدد من المركبات الفعالة للمستخلصات النباتية باستخدام التحليل النوعي للمركبات الكيميائية في النبات، اضافة الى التأثير العالي المضاد للأكسدة حيث سجل حوالي 64.84، بينما توصلت نتائج تقنية كروموتوغرافيا الغاز مركبات جديدة مختلفة في المستخلص المائي و الإيثانولي. كما أظهرت نتائج المستخلصات المائية والكحولية والخل والعسل لنبات C. myrrha أن جميع المستخلصات المدروسة لديها القدرة على تثبيط الزوائف الزنجارية ولكن في نطاقات مختلفة. أعطى المستخلص المائي نتائج أعلى من المستخلصات الكحولية والخل وكذلك العسل، أما العسل فلم يكن له تأثير تثبيط تآزري عند مزجه مع نبات المر. اما العصيات اللبنية اعطت تأثير مثبط للنمو في الأجار الصلب لجميع العزلات المختبرة ، بينما لم يظهر استخدام الراشح البكتيري أي نشاط مثبط ضد البكتيريا .
Received 27/09/2023
Revised 14/11/2023
Accepted 16/11/2023
Published Online First 20/04/2024
تفاصيل المقالة
هذا العمل مرخص بموجب Creative Commons Attribution 4.0 International License.
كيفية الاقتباس
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